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Campos' study did not stratify the diabetes patients in his study by how long they had been living with their disease. But researchers think the benefits of gastric bypass may indeed be greatest in those obese patients who are recently diagnosed with diabetes, since their bodies are more likely to revert back to normal sugar metabolism after surgery. That's because much of the post-bypass weight loss is spurred by a shift in the hormonal feedback loop that controls hunger and satiety. Production of certain weight-related hormones, such as ghrelin, or the hunger hormone, are directly reduced...

Author: /time Magazine | Title: Gastric Bypass Surgery Less Helpful for Diabetics | 9/16/2008 | See Source »

...landmarks unique to each patient to determine the size of his or her new, smaller stomach. But because the stomach lining remains elastic and flexible, sometimes the small stapled-off pouches simply balloon back to a larger size, which explains why 5% to 15% of people who get gastric bypass surgery often experience little or no weight loss...

Author: /time Magazine | Title: Gastric Bypass Surgery Less Helpful for Diabetics | 9/16/2008 | See Source »

...often considered a last resort for the severely overweight and obese, but gastric bypass surgery can be a lifesaver for one group of overweight patients: those with diabetes. Several recent studies have reported that the surgery not only reduces patients' risk of death - particularly from obesity-related diseases, including diabetes and coronary artery disease - but that in some patients with diabetes the surgery is practically a cure, resulting in normalization of blood sugar, often within days. That's part of the reason that gastric bypass is now the most commonly performed weight-loss surgery in the U.S., with nearly...

Author: /time Magazine | Title: Gastric Bypass Surgery Less Helpful for Diabetics | 9/16/2008 | See Source »

...study introduces a curious wrinkle in the evidence. Led by Dr. Guilherme Campos, director of the Bariatric Surgery Program at the University of California, San Francisco, the study found that gastric-bypass patients with diabetes did not lose as much weight as other patients after the surgery. Of the 310 patients in the study, 92% of those without diabetes were able to lose more than 40% of their excess weight - statistically, that's considered a successful procedure - while only 79% of diabetes patients were able to drop that much weight after one year. In both cases, doctors used the same...

Author: /time Magazine | Title: Gastric Bypass Surgery Less Helpful for Diabetics | 9/16/2008 | See Source »

...points out, may be to rely on newer anti-diabetes drugs, such as the DPP-IV inhibitors (like Januvia, the first to receive FDA approval), that can help patients keep their blood sugar and weight under control. "We can have even better results in controlling diabetes after gastric bypass surgery if we change the way we manage diabetes until these patients can get off their drugs," he says. (See photos of what makes you eat more food here...

Author: /time Magazine | Title: Gastric Bypass Surgery Less Helpful for Diabetics | 9/16/2008 | See Source »

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