Word: callicrein
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Dates: during 1965-1965
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...were festering sores on two of the technician's fingers, and some doctors were already recommending amputation. But Dr. Massart was reminded of other stubborn, non-healing sores that he had seen, mainly on aged and debilitated patients; he remembered that such sores had responded to injections of callicrein (Kallikrein in Germany and trade-named Padutin by Bayer), a byproduct of insulin extraction. Why not try the same stuff on the radiation sores? Medical scientists had always considered radiation burns distinct from all other types of injury. Naive or not, Dr. Massart figured that there was little to lose...
Within a few weeks the man's wounds were almost fully healed. Last month Dr. Suzanne Simon of Brussels University Hospital reported that, callicrein had worked equally well in 80 of the first 100 cases so treated. Even when it failed to heal the burns, it relieved pain more effectively than morphine...
Most surprising of all, no one yet knows the chemical structure of callicrein or how it works...
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