Word: cambodia
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...Global Fund's new plan proposes to solve this public-health crisis with a market-based solution. To undercut sales of counterfeits and alternative treatments, the Global Fund initiative will spend more than $220 million to subsidize genuine, effective combination-therapy drugs, and in Cambodia, it will spend an additional $10 million to ensure good distribution around the country. The idea was first proposed in 2004 by a committee of the Institute of Medicine headed by Kenneth Arrow, a winner of the 1972 Nobel Prize in Economics. The idea is that if the market is relied on to root...
...disease in the world, after HIV/AIDS and tuberculosis, and most of its victims are children. With the help of tens of millions of dollars from the Bill and Melinda Gates Foundation and various governments, the global health community - from biochemical engineers in Berkeley, Calif., to village volunteers in Battambang, Cambodia - is racing to eliminate the increasingly resistant parasite before it's too late. This week, the Global Fund signed off on a $220 million-plus project called the Affordable Medicines Facility for malaria (AMFm), a controversial two-year program that will drop the price of the recommended malaria treatment...
...clears out the parasite in less than 72 hours but doesn't remain in the body, artemisinin is prescribed with a slower partner drug to clean out any straggler parasites that might have developed resistance. Taking a partner drug with artemisinin, called combination therapy, is required by law in Cambodia and Thailand, but it's difficult to enforce. Since the partner drug - typically mefloquine in Southeast Asia - has more side effects, some people take only the artemisinin pills. This may work to clear out the parasite for one person, but it leads to rapid drug resistance when the practice...
Every year, hundreds of migrant workers arrive at makeshift sapphire and ruby mines near Pailin, Cambodia, risking their lives to unearth gems in the landmine-ridden territory. Soon, however, they could be the ones to put millions of others at risk. On the Thai-Cambodian border, a rogue strain of malaria has started to resist artemisinin, the only remaining effective drug in the world's arsenal against malaria's most deadly strain, Plasmodium falciparum. For six decades, malaria drugs like chloroquine and mefloquine have fallen impotent in this Southeast Asian border area, allowing stronger strains to spread to Burma, India...
...Modeling by the Mahidol-Oxford Tropical Medicine Research Unit published in the Malaria Journal in February predicts that if nothing is done in the next two decades, "resistance to artemisinins will be approaching 100%." And if that happens, it won't be long until the resistant strain spreads from Cambodia's precious gem mines to Africa, putting half the world's population at risk of catching what would be an untreatable, deadly disease...