Word: canarypox
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...vaccine was administered in two stages. First the ALVAC vaccine, which uses a Frankenstein virus of canarypox and HIV, was used as a primer dose, then AIDSVAX was administered as a "booster" to improve the body's immune response to the first shot. Half of the trial's participants received the combination vaccine, while the other half received a placebo. In the final analysis, 74 of the 8,198 placebo recipients became infected with HIV, compared with 51 of 8,197 participants who received the vaccine regimen...
...about two dozen vaccines have been tested, most made from proteins found on the virus' coat and delivered via another, inactivated virus such as canarypox. While such vaccines are safe and successful in triggering antibodies, it's not clear that any will be sufficiently powerful to combat the strains of the virus that are currently in circulation...
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