Word: cancer
(lookup in dictionary)
(lookup stats)
Dates: during 1970-1979
Sort By: most recent first
(reverse)
DIED. Luther W. Youngdahl, 82, unflappable federal judge who in three famous rulings bucked the Government's anti-Communist zeal of the 1950s; of cancer; in Washington, D.C. Youngdahl, a deeply religious son of Swedish immigrants, was appointed to the bench in 1951 after five years as a racket-busting Republican Governor of Minnesota. In 1952 he drew a Government perjury case against Asia Expert Owen Lattimore, whom Senator Joseph R. McCarthy called "the top Soviet espionage agent in the United States." Youngdahl threw out several Government indictments against Lattimore, refused to withdraw from the case when...
Researchers have long been frustrated by their inability to get cancer cells from patients' tumors to grow rapidly in culture. But the Arizona team, led by Dr. Sydney Salmon and Cell Biologist Anne Hamburger, discovered three years ago that by "conditioning" culture medium with spleen cells taken from mice prone to cancer, they can grow tumor cells from people with common forms of cancer. (The mouse cells apparently produce some yet unidentified factor that supports the growth of certain human cancer cells.) According to Salmon, the cancer cells that thrive and form colonies in the laboratory's plastic...
...cells taken from tumors and then culturing the cells in order to, in their words, "determine whether there are correlations between what is observed in the petri dish and in the patient." Tumor cells taken from nine people with myeloma, a bone marrow malignancy, and nine with ovarian cancer were exposed to varying concentrations of several anticancer drugs, then cultured in petri dishes. The researchers compared the effects of the drugs on the cultured cells with the patients' responses to the same drugs. In all but one case, the effects matched. If the drug prevented cancer cells from growing...
...main value of the laboratory test, says Salmon, is that it can help the physician plan individual courses of treatment. For example, only 20% of people with cancer of the colon or rectum respond to the drug fluorouracil; the other 80% suffer needlessly from the drug's toxic effects. The new technique may have another benefit: it could be used to evaluate new anticancer drugs without endangering cancer patients...
...every hospital. Until it has had adequate testing, it should be considered only a promising research tool." Still, that promise is exciting. A Journal editorial accompanying the paper notes that "an effective and practical predictive test for antitumor agents would have a profound effect on the treatment of cancer...