Word: cancerous
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Dates: during 1980-1989
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...under development that can be embedded in a woman's thigh or arm and will automatically dispense contraceptive hormones for a year. Researchers at the Massachusetts Institute of Technology are experimenting with dissolvable plastic wafers that are implanted in the brain and slowly release an antitumor drug for cancer victims. The day is not far off when most diabetics will be able to give themselves insulin with a nasal spray. In California doctors are working on drug-loaded bubbles of fat that bind themselves to diseased cells. Says Robert Langer, a biomedical engineer at M.I.T.: "It's an explosive field...
...coated pills and small adhesive skin patches capable of delivering doses of medication. The new drug-delivery systems, based on advances in molecular biology, represent a dramatic improvement over their predecessors. Take the plastic wafer, about the size of a quarter, that can carry powerful drugs to brain-cancer victims. Researchers have known for some time that disks formed of chemical structures called polymers work well for dispensing small molecules like nitroglycerin, a pain reliever commonly used for heart patients. But the polymers seemed stubbornly resistant to releasing larger molecules of substances like insulin and growth hormones in the slow...
While the polymer and spray systems stress control and timing, others -- such as those being tested at the Cancer Research Institute of the University of California at San Francisco -- attempt to deliver specific drugs to specific cells. To accomplish this, microscopic bubbles of fat, called liposomes, are filled with a cancer drug and attached to antibodies that have the ability to distinguish cancer cells from healthy cells. Injected, the package ignores normal cells and attaches to diseased ones. But getting the liposomes to stay in the blood long enough to do their job has been difficult until now. Researchers seem...
Obscene as cancer, bitter...
DIED. Elmo R. Zumwalt III, 42, whose father, Admiral Elmo R. Zumwalt Jr., ordered that riverbanks in Viet Nam be sprayed with Agent Orange to protect U.S. sailors, including his son, from ambush; of cancer; in Fayetteville, N.C. Both the former chief of naval operations and his son contended that the illness was caused by the defoliant. "Knowing what I know now," wrote the father after his son fell ill, "I still would have ordered the defoliation. But that does not ease the sorrow I feel for Elmo...