Word: cancerous
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Dates: during 1990-1999
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...widely heralded but still experimental cancer-fighting compound may be used someday to prevent two other major killers of Americans: heart disease and stroke. That was the implication of a remarkable report published last week in the journal Circulation by a team of researchers from Dr. Judah Folkman's laboratory at the Children's Hospital in Boston...
...versatile compound is endostatin, a human protein that inhibits angiogenesis, the growth of new blood vessels in the body. In tests reported in 1997 by Folkman, a prominent cancer researcher who pioneered the study of angiogenesis, the drug had reduced and even eradicated tumors in laboratory mice. How? By stunting the growth of capillaries necessary for nourishing the burgeoning mouse tumors...
When news of Folkman's achievement became widely known last year, it led to wildly exaggerated predictions of imminent cancer cures. When other scientists were initially unable to duplicate those results, questions arose about the validity of Folkman's research. Then in February scientists at the National Cancer Institute, with guidance from Folkman, finally matched his results. Reassured, the N.C.I. gave the go-ahead for clinical trials of endostatin later this year on patients with advanced tumors...
Kids who smoke like to think that they're immortal--or at least that if they stop in time, their lungs will heal. But a report in last week's Journal of the National Cancer Institute suggests early smoking may trigger changes in DNA that put young smokers at higher risk for cancer even if they later quit. Researchers studying lung-cancer patients found that those with the worst genetic damage were not those who smoked longest but those who started youngest. What's more, the earlier they started, the more severe the damage...
...members of Congress, whose duty is to represent the American people, would get the point. Allegations of foreign tampering in U.S. elections and unbelievable fund-raising techniques by the Clinton administration should have been enough to outrage Republican diehards. The efforts of tobacco lobbyists to evade responsibility for lung cancer deaths by paying off representatives should have Democrats screaming bloody murder. Instead, there is only silence...