Word: cancers
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Dates: during 1990-1999
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Despite the confused coverage of Folkman's work in the media, Ingber says endostatin has the potential to one day be a very important weapon in the fight against cancer and other diseases...
...media wants a silver bullet, but it is virtually impossible to obtain one, especially given how cancer trials are designed...using end-stage patients who have failed all other therapies with large tumor mass, et cetera," he says...
...Since the drug must be given alone in Phase I so that the results are interpretable...no one has seen one hundred percent of tumors regress and disappear when these drugs are given alone," he says. "These are often end-stage cancer patients with tumors that have become modified by many past chemical and radiation therapies...
However, from his own work and observation of Folkman's work, Ingber says he believes in the end angiogenesis inhibitors will help in the management of cancer and other disorders...
...firm believer that cancer will not be cured per se,"he says. "Rather it will be managed much like we now manage tuberculosis or diabetes. In sum, if [anti-angiogenesis therapy] is not a cure it will break the back of the disease...