Word: cancers
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...doctors may have to become molecular chefs, cooking up new anti-cancer recipes with a growing number of promising drug ingredients. If the number of presentations at ASCO is any indication, their lab cupboards are plenty full of just such compounds. So far, the best cocktails, still in early testing in the most advanced cancer patients, try to include some agents aimed at cutting off a tumor's blood supply (so-called angiogenesis inhibitors), others designed to trigger a cancer cell's pre-programmed suicide pathway, or still other compounds that muck up the intricate signaling system that a cancer...
...Sikic, a professor at Stanford University School of Medicine who chaired the committee that designed ASCO's program. "It's correct that there were more Phase I studies in the clinical science symposia," he told me. "And we did that deliberately. It was a way to inform both practicing [cancer doctors] and clinical researchers about early data and the scientific background of new targets. We now have a huge amount of scientific research and much more knowledge in depth of why we should be targeting a particular gene or protein and how these drugs might work...
...this is good news for patients, as long as they remember that, as promising as drugs sound in Phase I, they still have a long way to go before they make it to the pharmacy, if they make it at all. But with more candidates in the cancer kitchen, better cocktails are bound to emerge. "For those of us in cancer research, it's a very exciting time," says Sikic. "And we're hoping that with every year, it's going to be a better and better time to be a cancer patient...
...from sweetened, packaged "fruit" products- such as fried banana chips- which can be high in saturated fat and contain far more sugar than the fruit they're derived from. "They're not far away from regular candy," says Tim Radak, a nutritionist and program manager at the Northern California Cancer Center. "They may throw in fruit juice and call them fruit snacks, but they're quite far from a real piece of fruit...
...little or no effect in slowing bone loss, even / when the dosage was as high as 3,000 mg per day. The most effective defense against osteoporosis in these women, all agreed, is estrogen replacement. Such therapy has been linked in the past to an increase in endometrial cancer, but doctors now believe the risk can be minimized by tandem use of progesterone- like hormones...