Word: cancers
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...should reassure a lot of women. There is still no scientific justification for the long-term use of hormones after menopause to prevent such conditions as heart disease or dementia. But a shorter course of estrogen--seven years or less--is safe enough with respect to breast cancer and other health risks that it's a reasonable option for the treatment of severe menopausal symptoms. In other words, says Marcia Stefanick, one of the lead researchers, since there is no overriding safety concern, "the focus should be on your individual risk...
Here's where things get tricky. A closer look at the findings shows that women who have had a benign breast ailment, who score high on the so-called Gail model of breast-cancer risks or whose mother or sister had breast cancer are slightly more likely to develop breast cancer when taking estrogen supplements. In addition, all study participants, regardless of their breast-cancer risk, were more likely to have suspicious-looking mammograms that required biopsies to make sure that nothing was wrong...
...have severe menopausal symptoms, have lost your uterus and don't have a high risk of developing breast cancer or blood clots, you can safely consider estrogen therapy for temporary relief. Eventually, as genetic tests based on blood samples from WHI participants start to be developed, investigators should be able to say even more precisely who is likely to benefit from estrogen treatment and who should avoid it. Meanwhile, stay tuned for more surprising WHI results...
...that cell that is suddenly sparking the interest of cancer researchers and molecular biologists around the world. Known as a cancer stem cell, it could be the culprit behind a malignant tumor's nasty habit of recurring year after year and popping up in distant parts of the body long after the primary growth is gone. Studies of that cell are helping scientists unravel some of cancer's deepest secrets and leading doctors closer to the ultimate goal of any cancer therapy--a cure. Think of the stem cell as a tumor's master print; as long as the original...
Those ideas are already changing the way doctors think about cancer. They are starting to set aside their decades-old obsession with reducing the bulk of a cancerous growth and appreciate instead that the vast majority of its mass is cellular noise, a distraction from the tiny percentage of cells--perhaps as few as 3% to 5%--that are the real culprits. At the latest meeting of the American Association for Cancer Research, researchers at City of Hope Cancer Center in Duarte, Calif., announced that they had isolated a group of stem cell--like cells in lungs that seed...