Word: cancers
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DIED. MARY ELIZABETH CRONKITE, 89, wife of former CBS anchorman Walter Cronkite, known as Betsy; of complications from cancer; in New York City. As employees of radio station KCMO in Kansas City, Mo., the pair met on Betsy's third day at work when they stood near each other to read advertising copy on the air. The couple would have celebrated their 65th wedding anniversary this month...
...that's exactly what Dr. Stephen Russell was hoping for. A cancer specialist at the Mayo Clinic, Russell does everything he can to aid and abet those viral bandits. He arms them with detailed instructions for finding their target cells and outfits them with specially designed protein keys to speed up entry. As far as he's concerned, those viruses are the good guys, since the cells they are attacking and destroying are cancer cells in a fast-growing tumor...
...good-bug strategy was championed by doctors treating allergies and infectious diseases. The idea was to expose patients to small quantities of partly disabled microbes to jump-start their immune system. But cancer researchers have taken the approach one step further, turning microbes into tiny Trojan horses that can sneak into tumor cells and destroy them from within. "There is a good probability that microbe approaches will be part of the arsenal of the future," says Kenneth Kinzler, a cancer researcher at Johns Hopkins Hospital's Kimmel Cancer Center who is working with the clostridium bacterium. "We're betting...
...flourished briefly in the 1960s, during the early days of the genetic revolution. Scientists sketched out grand plans for treating disease by adding or removing genes taken from bacteria or viruses. Because they were so good at penetrating cells, infectious agents seemed the ideal vehicles for delivering drugs. Some cancer patients were treated with experimentally modified viruses, and a few even saw their tumors shrink. Too often, however, scientists lost control of their microbial partners. "It wasn't possible at the time to engineer them to make them more specific," recalls Russell. "When they did work, there was a price...
...gifts and attention on them and provided them an SUV and rides in limousines. Gradually, the accuser said, Jackson's fascination waned, even as the boy's condition worsened. He testified that the singer hid when the boy visited the ranch. A year later, in a near miracle, the cancer was declared to be in remission. No evidence of it has returned...