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...Alzheimer's fug in a Melbourne retirement village, garnered his Claymation creator a nod for Best Short Film (Animated) at next week's Academy Awards ceremony. Up against toon titans Pixar, Disney and Blue Sky, Elliot and his tragicomic creation, who endures Tourette's syndrome and testicular cancer before seizing the day as an avid animal liberationist and nudist, is perhaps the ultimate underdog. (Seven years ago, an Oscar went to a similarly off-kilter outsider - Shine's Geoffrey Rush, whose presence as Harvie Krumpet's narrator lends the film an added poignancy.) "I deal with characters who are different...

Author: /time Magazine | Title: Pathos in Plasticine | 2/23/2004 | See Source »

...older, my auntie drank rat poison and died," says the narrator of Uncle, which sets the tone in the Elliot oeuvre for outlandish deaths. As for the carnage in Krumpet, Harvie's parents are found frozen naked on their bike, Dr. Angela Greystane dies horribly from emphysema, the cancer-ward nurse Harvie marries collapses from a brain clot, fellow retiree Wilma overdoses on morphine - and that's not counting the animals. "Yeah, I've got a high body count," the filmmaker says. Which makes Harvie's survival all the more remarkable - and affecting...

Author: /time Magazine | Title: Pathos in Plasticine | 2/23/2004 | See Source »

What does a stubbed toe or a splinter in a finger have to do with your risk of developing Alzheimer's disease, suffering a heart attack or succumbing to colon cancer? More than you might think. As scientists delve deeper into the fundamental causes of those and other illnesses, they are starting to see links to an age-old immunological defense mechanism called inflammation - the same biological process that turns the tissue around a splinter red and causes swelling in an injured toe. If they are right - and the evidence is starting to look pretty good - it could radically change...

Author: /time Magazine | Title: Health: The Fires Within | 2/23/2004 | See Source »

...chronic inflammation does harm to the body. It destabilizes cholesterol deposits in the coronary arteries, leading to heart attacks and potentially even strokes. It chews up nerve cells in the brains of Alzheimer's victims. It may even foster the proliferation of abnormal cells and facilitate their transformation into cancer. In other words, chronic inflammation may be the engine that drives many of the most feared illnesses of middle...

Author: /time Magazine | Title: Health: The Fires Within | 2/23/2004 | See Source »

This concept is so intriguing because it suggests a new and possibly much simpler way of warding off disease. Instead of different treatments for, say, heart disease, Alzheimer's and colon cancer, there might be a single, inflammation-reducing remedy that would prevent all three...

Author: /time Magazine | Title: Health: The Fires Within | 2/23/2004 | See Source »

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