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...amyloid that forms in the brain; but another variant of the gene may also allow amyloid to form fibrils, the sticky protein arms that further anchor amyloid plaques to nerve cells, much like a spider web ensnares prey. In late-onset Alzheimer's, it's possible that the body cannot balance these two functions of clusterin. "It may be that the difference between a variant of clusterin that protects from Alzheimer's versus one that has a higher risk is the balance between clearing amyloid versus causing it to form more deposits," says Dr. Alison Goate, an author...
...This isn’t a solution we can live on. We need to do something that will bring cost under control,” Weingarten said of the Republicans’ plan. “We cannot afford to let insurance companies play with our lives and our money as they continue to cover less for more with no incentive to change...
Although the new findings in Obesity cannot yet be applied outside the lab, other research supports the idea that the disruption of sleep (that includes standing in front of the fridge eating chicken at 2 a.m.) may have something to do with weight gain in humans. Studies of night-shift workers like nurses and factory workers indicate they are at higher risk for being overweight than their daylight counterparts, partly due to poor sleep routines and partly because of their tendency to eat heavy meals late at night, says Aronne. Other studies show that people who get a full eight...
...accepted as conventional wisdom, they seem to be headed for trouble in the courtroom where the fine reading of law comes into play. Judge Aharon Farkash, who has a degree in archaeology, has wondered aloud in court how he can determine the authenticity of the items if the professors cannot agree among themselves. (Read a story from TIME's archive on the ossuary of James...
...Shiva Naipaul’s cynical yet deeply moving account of a late 1970s journey through East Africa, without being reminded of the travel writings of his legendary elder brother, V.S. Naipaul. Only 40 when he died of a heart attack in 1985, the unfortunate younger Naipaul cannot escape comparisons to his sibling, older by 13 years and a literary behemoth and Nobel Laureate often described as Britain’s greatest living writer. Shiva Naipaul’s work is more than worthy of notice on its own merits, but in so far as he has been remembered...