Word: cantley
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Dates: during 2000-2009
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Anthrax toxins were proven lethal in 2001, after five individuals died as a result of exposure to anthrax spores contained in a series of mailings across the U.S., according to Lewis C. Cantley, senior author of the study and chief of the Division of Signal Transduction at Beth Israel. The deceased victims were successfully rid of anthrax bacteria by antibiotics, thus proving that buildups of anthrax toxin—which would not have been counteracted by the antibiotics—must have been the cause of death...
Avanir’s antibiotic would be more powerful and possibly more effective than the current anthrax vaccines that require booster shots every year to remain potent and that combat only anthrax bacteria. But unlike the Avanir antibiotic, Cantley said he hoped that a drug designed to inhibit anthrax lethal factor would be effectively administrable after contraction of anthrax, thereby lessening the need to inoculate large populations and saving lives in cases of late diagnosis...
...drug we envision could inhibit the toxin even after the toxin is released into the cell,” Cantley said. “It could be administered successfully in what you might call the late stages of lethality...