Word: cantley
(lookup in dictionary)
(lookup stats)
Dates: all
Sort By: most recent first
(reverse)
According to Cantley, the next stages of drug development will involve experimentation on mice, which can be performed in an academic setting...
...Cantley said that under normal circumstances, the development of an FDA-approved drug following the identification of key molecules would take approximately 10 years. But the process might be speeded somewhat in this case, he said, because of the U.S. military’s fear that inhalation anthrax, the most devastating form of the disease, might be used in a biological attack against major cities...
Pharmaceutical companies would not ordinarily be interested in pursuing a drug to combat anthrax toxin because of the low likelihood that an average person would be exposed to anthrax, Cantley said. But because of the prospect of obtaining lucrative government contracts, private companies have already expressed interest in creating such a drug, he added...
Private companies may also be encouraged about their chances of developing a successful drug because protease inhibitors have thus far proven the best method to slow the progress of HIV infection, Cantley said...
...study also yields hope because the potential protease inhibitors identified have a high degree of what Cantley called “bioavailability,” or effectiveness in reaching target sites. The molecules that stopped the spread of anthrax toxin in the clinical study are between 0.5 and 5 micrometers in size—small enough to be able to permeate a human cell membrane...