Word: canvaxin
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Dates: during 2000-2009
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...vaccine. After all, infection plays no role in cancer, except in a few rare types of malignancy. And a cancer cell, unlike an invading pathogen, isn't wholly foreign to the body. Nevertheless, researchers are learning that the immune system can even be trained to go after tumors. CanVaxin, for example, a vaccine for the deadly skin cancer melanoma, is made from cancer-cell lines taken from three different patients; among them, they express more than 20 disabled tumor antigens that the immune system can learn to recognize...
Indeed, in early clinical trials on people whose tumors had been surgically removed, those receiving the vaccine lived on average twice as long as controls. To make the vaccine even more potent, company scientists are testing a version of CanVaxin enhanced with cytokines to help boost the response of patients with immune systems damaged by chemotherapy. In Canada a vaccine called Melacine, made by Corixa, is also fighting melanoma, shrinking tumors as effectively as chemotherapy but with fewer side effects. It is currently in trials...
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