Word: cardiovascular
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...these cases," he says. He notes that the stimulants in question are known to raise blood pressure and heart rate. "Raising blood pressure of a child or adult continuously over many years worries me," Nissen told TIME. "There is a linear relationship between increased blood pressure and adverse cardiovascular events." Nissen further notes that two stimulants that are related to the Ritalin class of drugs-ephedra and phenylpropanolamine (PPA)?have been banned from the market because of cardiovascular risks...
...warning. "I don't argue that there are some kids who need that treatment, but it's probably overused." Doctors Furberg and Nissen are also concerned about the rising number of adults on these drugs. About 10% are over 50, a group that has a higher rate of cardiovascular problems to begin with. Says Dr. Nissen: "I want the physicians' hands to tremble a bit when they write a prescription for these drugs...
...clearly wasn't expecting such a bomb to go off in a routine meeting, but now the agency must deal with the fallout. A black box warning is unlikely. "We don't feel the risk is well enough established," said Dr. Laughren. But studies of the cardiovascular effects of these drugs are likely to get underway, and, given how many Americans are already taking them, they are probably long overdue. The FDA will also weigh a unanimous recommendation by the panel to make potential risks to the heart more apparent in the patient guides given out by pharmacies. That topic...
...also possible that if you want to prevent cardiovascular disease, it?s not enough to focus just on the total amount of fat in the diet; you also have to look at the types of fat-particularly saturated and trans fats-as well as exercise and physical activity levels. Why didn?t the study focus more intently on these variables? Researchers were not as aware of how important they were back in the late 1980s, when they were designing the trial...
...Lancet work involved research that concluded that common painkillers like ibuprofen could help reduce the risk of oral cancer among smokers-although at the risk of dying from cardiovascular problems. The research in the New England Journal papers had to do with the potential use of DNA tests to determine the severity of oral cancers and precancerous lesions...