Word: caskey
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Dates: during 1990-1999
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...estimated 200,000 DNA profiles are run each year by states trying to document child-support or welfare payments, folks with paternity issues rarely have the wherewithal to order up a test on their own. About five years ago, however, that started to change. It was then that Caroline Caskey, 32, a French-literature major turned business student, thought to combine cutting-edge DNA analysis with old-fashioned, hawk-the-product marketing. A few years earlier, a lab headed by her father Thomas Caskey patented something called the "short tandem repeat," a shortcut method of sampling DNA. Caskey...
...such niceties carry little weight for people desperate to establish something as consequential as paternity, and Caskey plans to keep cashing in on that need. Identigene is preparing to offer an even cheaper, $150 test that will profile newborns' DNA to reassure anxious parents that they're leaving the hospital with their own child. "It's potentially a much bigger market than paternity testing," says Caskey. And a bigger payoff...
...technology and gene discoveries to develop an array of novel drugs. "Now that we have an increasing ability to identify and sequence genes, there is no doubt that there will be an improvement in the way we go about drug development," says Dr. C. Thomas Caskey, senior vice president of basic research at Merck, in Whitehouse Station, New Jersey...
...example, explains Caskey, researchers know that there are at least three or four forms of Alzheimer's disease, each of which may be caused by a different defective gene. "If I develop a drug for gene A," he says, "it may not have any influence on a patient who has a defect on gene C. So it's easy to understand how genomics research would be critical to the development of very precise and effective drugs...