Word: catalona
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Dates: during 1990-1999
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...most often strikes men who are in their 60s or 70s, more of them are now afflicted. When the baby-boom generation matures, the number will balloon. "As men live longer and do not succumb to heart disease and stroke, more will die from prostate cancer," says Dr. William Catalona, a urologist at Washington University in St. Louis, Missouri. "And it is not a nice death...
...strategy is to make use of the large bank of prostate tissue gathered by Washington University's Dr. Catalona and Dr. Paul Lange of the University of Washington, both members of the consortium. Researchers in Hood's lab plan to test every one of the consortium's variety of 600 tumor cells along with normal prostate cells collected at every stage of human development. Then they will use genetic-engineering techniques to produce markers that can identify tumors that are dangerous and those that are not. The same approach, he says, may eventually be used to identify many other kinds...
...protein called prostate-specific antigen, or PSA, will soon be offered to men over 50 who are at special risk for the disease, including blacks and those with a family history of the ailment. Some experts contend that all older men should be tested. Predicts lead author Dr. William Catalona, at Washington University in St. Louis: "PSA should dramatically alter the statistics on prostate cancer...
...method is by no means foolproof. Catalona stresses that 21% of the men in his study with prostate cancer actually had "normal" PSA levels. Thus the test should be used only in combination with a rectal exam, he said, and even then some cancers will be missed...
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