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...peanut oil is disseminated slowly through the body, keeping the penicillin content of blood high for hours. The Public Health Service acted swiftly. To 137 doctors throughout the land went instructions and the penicillin mixture with the request that they try single injections of 200,000 units (2 cc.) on as many patients as possible and report the results. Back came results on 1,060 cases: over 91% apparently cured, regardless of sex, color or stage of the disease. Many of the failures were cured by a second injection. The rest were re-treated-and nearly all cured-by slower...
...plasma at the front line and on the way to the field hospital. But when he arrived at the hospital he was almost dead. A four-way infusion was begun. In two and a half hours, the marine got twelve units of plasma, eleven pints of blood, 1,000 cc of saline and glucose. That stabilized his blood pressure for his operation, after which he was given three units of plasma and two of blood. He lived...
Dramatic Relaxation. Two years ago, Dr. Griffith began using curare on patients (especially abdominal cases) whose muscles remained tense in spite of general anesthesia. He was delighted at the "dramatic and complete relaxation" produced by the contents of one 5-cc ampoule injected into a vein. The effects are at maximum in five minutes, usually last 20 minutes...
...have developed a greenish, minty chewing gum, containing 3¾ grains of sulfathiazole in each "tablet." According to last week's Apothecary, a patient who chews the gum for 30 minutes to an hour gets a high concentration of the drug in his saliva (70 milligrams per 100 cc. of saliva; the concentration used in the blood in acute pneumonia is only five to ten milligrams per 100 cc.). Although the concentration is high in the saliva, very little gets into the blood stream and "there is but slight possibility of any systematic toxicity"-i.e., the sulfa...
...skin had no effect on Tom's gastric mucosa. But when a spot on his stomach lining was stripped of its protecting mucus and sprinkled with mustard, it became very sensitive. Strong pressure with a glass rod or from a balloon inflated in his stomach to 1,500 cc. gave Tom a stomachache...