Word: ccr3
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Dates: during 1990-1999
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Gabuzda used this discovery to try to find out if any of these proteins allowed HIV into microglia. She found that CCR5, and another protein--CCR3--are part of the complex that is the brain's gate...
These molecules had been suspected of being able to channel HIV "but this had only been suggested in recombinant DNA experiments," says Gabuzda. "This is the first time CCR3 has been shown to be the doorway...
...known that people who are deficient in the CCR3 receptor show no known abnormality, and further that they are highly resistant to HIV infection," says Gabuzda...
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