Word: ccr5
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Dates: during 1990-1999
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...course, now that we know the extent of HIV's nastiness we can get a lot closer to defeating it. The little hook that HIV uses to bind itself to cell receptor CCR5, for example, could be the virus' Achilles' heel. Blocking that hook may be the key to preventing HIV's ability to infect. "There's no question we're better off now than we were before," said Sodroski. "Before we were blind, now we are sighted." And that's a miracle in itself...
Last year, Associate Professor of Pathology Joseph G. Sodroski found two other gate proteins that HIV uses to enter cells in the rest of the body--CCR5 and CXCR4...
Gabuzda used this discovery to try to find out if any of these proteins allowed HIV into microglia. She found that CCR5, and another protein--CCR3--are part of the complex that is the brain's gate...
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