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That's true also for the use of over-the-counter painkillers like ibuprofen and naproxen, and other non-steroidal anti-inflammatory drugs (NSAIDs) like Celebrex (celecoxib). Guidelines written and published by the American Geriatrics Society warned against using these drugs chronically and at moderate-to-high doses in patients age 75 or older with persistent pain. Citing the many risks of long-term NSAID use, including fatal ulcers and gastrointestinal bleeding, increased risk of heart attack and stroke and dangerous interactions with other drugs commonly prescribed to the elderly, the American Geriatrics Society suggested that seniors try acetaminophen instead...

Author: /time Magazine | Title: Are Doctors Too Reluctant to Prescribe Opioids? | 2/24/2010 | See Source »

...Automation should eliminate many of the errors that occur when pharmacists misunderstand or misrecord medication names or dosages conveyed messily on paper or hurriedly by phone. Given that there are more than 17,000 pharmaceutical brands and generics available, a spoken request for Celebrex, for instance, can be mistaken for Celexa, or a notation requesting 150 milligrams of a drug might be read as 1500. In electronic systems, drugs and dosages are selected from menus to prevent input errors, and pharmacists don't need to re-enter information...

Author: /time Magazine | Title: Cause of Death: Sloppy Doctors | 1/15/2007 | See Source »

...What a contrast to my next patient. Sean is half Bob's age. He weighs less, isn't as active, and has nice straight legs. Barely a trace of arthritis on X-ray and nothing except "minimal arthritic changes" on his MRI. He has taken Advil, Naprosyn, Voltaren, Celebrex with minimal help. Injections into his knees of hyaluronic acid (a component of joint fluid) and corticosteroids provided only a few weeks of relief. Physical therapy, braces, acupuncture, yoga all failed. He couldn't get out of chairs, couldn't climb stairs because of the pain. There was one thing left...

Author: /time Magazine | Title: The Mystery of Pain | 9/8/2006 | See Source »

...what's a corporate lawyer doing atop the world's largest drug company? Saving it in court. The company is facing a flood of legal challenges. Among them: drugmaker Novo Nordisk recently claimed patent infringements for Pfizer's upcoming inhaled-insulin drug, Exubera, and Pfizer is being sued over Celebrex, its controversial Cox-2 inhibitor pain medication. Bonus points: Kindler knows his way around Washington, which should help Pfizer navigate the regulatory swamp. He has some operations cred too. At McDonald's, he led the turnaround of Boston Market...

Author: /time Magazine | Title: People to Watch In International Business | 8/20/2006 | See Source »

...wasn't bad enough losing to a guy who belongs in a Celebrex ad, American Idol's KATHARINE MCPHEE has fallen victim to the curse of the Idol runner-up--a bum foot. The show's 2004 No. 2 Diana DeGarmo slipped down a flight of stage stairs, tearing a ligament. Last year Bo Bice broke his foot during some rigorous onstage bouncing. And now McPhee has tripped backstage, fracturing her left foot. All of which makes us wonder what those singers need more: to prove Simon Cowell and America wrong or to wear slightly more sensible shoes...

Author: /time Magazine | Title: People: Aug. 14, 2006 | 8/6/2006 | See Source »

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