Word: celles
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Hwang Woo-Suk, the Korean scientist who gained international media attention for making fraudulent claims about cloning a human embryo, may have inadvertently made a significant breakthrough in stem cell research, a team of scientists led by a Harvard professor announced last week...
George Q. Daley, an associate professor at Harvard Medical school and a member of the Harvard Stem Cell Institute (HSCI) Faculty Executive Committee, led the team that studied Hwang’s research. They determined that Hwang produced human stem cells through parthenogenesis, a process whereby an unfertilized egg begins to divide through external stimulation...
Scadden said that this area of study would be limited, however, both because it would only allow for stem cell lines from women and because it doesn’t allow scientists to create “disease-specific” stem cell lines...
...terms of being useful as a replacement cell type, [parthenogenesis] can be advantageous,” he said. “But if you want to create cell lines that might be representative of all of the genetic components in someone who has a disease like ALS, for example, you need to do nuclear transfer...
Scadden said that this process of somatic nuclear transfer—essentially taking a nucleus from a skin cell, transferring it into an egg, and then prompting the egg to divide—would allow scientists “to have in a petri dish a model of these complex diseases for which we have very little therapy...