Word: celles
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...expected those opportunities to come so soon. Trying to discover the right combination of genes that would reprogram adult cells was a scientific fishing expedition in a deep ocean. In early 2004 Yamanaka had worked up a list of 24 possible genes he thought were instrumental in cell programming, and was ready to begin testing them. There was no guarantee any of the 24 suspects were the right ones, and when Yamanaka offered the experiment to one of his students, the researcher turned him down. "We knew the chance that the correct answer was in those 24 factors was very...
...Yamanaka. Scientists had assumed that reprogramming would likely require a complex arrangement of far more genes. "We were very surprised," he says-and with the Hwang debacle on their minds, "we were very worried." Yamanaka had another researcher repeat Takahashi's work, and when they published in the journal Cell in August 2006, he took the unusual step of including every last bit of lab data in the supplementary section of his paper. Still, Yamanaka's results weren't fully accepted until his work was replicated by others-the gold standard of scientific proof...
...that Yamanaka has helped show science the path, the race is on to discover the researcher's holy grail: a way to reprogram adult cells in human beings. The Japanese pioneer finds himself at a disadvantage. Scientists in the U.S. and Europe can draw on deeper reserves of money and talent. U.S. states such as California and Massachusetts are spending billions of dollars on stem-cell research, hoping to lay the groundwork for development of new medical industries. In contrast, Yamanaka's lab at Kyoto is relatively basic, and the Japanese government has only recently begun channeling real funding into...
Even without such sophisticated genetic work, doctors can now learn more about how treatment is progressing simply by tallying the number of circulating cancer cells and better understanding what that head count means. At the ASCO conference, researchers from the U.S., Britain and the Netherlands reported that after about a month of treatment, patients who had advanced prostate and colon cancers and lower circulating cell counts survived an average of twice as long as those who had higher levels. More cells in the blood could be a sign that the drugs are not working and that it's time...
Walt Disney chief executive Bob Iger is the antithesis of a brash showman. At last January's Consumer Electronics Show, a high-tech hype-fest in Las Vegas, another CEO peddled a two-wheeler onstage to tout his company's new bicycle-powered cell-phone charger. The understated Iger, wearing spectacles, a dark suit and white shirt, talked about strategy and happily let Pirates of the Caribbean producer Jerry Bruckheimer, ESPN commentators and Lost cast members take the lead in unveiling Disney's multimedia-entertainment fare...