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...hard to find any scientist today who believes him. Even if Hwang's two remaining triumphs, Snuppy and the first human cloning, emerge untainted, urgent questions remain. How did his now invalidated stem-cell paper get into a major scientific journal? How did such serious flaws go undetected for months? And could he have knowingly taken such foolish risks...

Author: /time Magazine | Title: The Rise and Fall of the Cloning King | 1/1/2006 | See Source »

Evidently, the risk-taking began in 2004, with Hwang's first major scientific paper on therapeutic cloning. In order to clone an adult, you need to put one of its cells into a human egg cell from which the nucleus has been removed. After electrical fusion and chemical activation, the egg can then start dividing, creating embryonic stem cells. (If left to mature, the embryo could eventually grow into a clone of the original adult--something no reputable scientist would let happen...

Author: /time Magazine | Title: The Rise and Fall of the Cloning King | 1/1/2006 | See Source »

...same time, Korea's vibrant Internet culture started buzzing with allegations by two anonymous posters that photos in the 2005 paper purported to be of different stem-cell cultures were in fact identical, and that DNA fingerprints used to prove that the stem cells were derived from clones seemed suspicious. In retrospect, says Dr. Katrina Kelner, a deputy editor at Science, "these looked too clean" to be legitimate...

Author: /time Magazine | Title: The Rise and Fall of the Cloning King | 1/1/2006 | See Source »

MizMedi's Roh, meanwhile, says that after a visit to Hwang at the hospital, he was convinced that "there are no embryonic stem cells." In response to Hwang's retraction, the university finally launched its investigation and announced last week that there is no evidence that any of the stem-cell lines Hwang claimed he had derived from adult cells ever existed (the full report is expected in mid-January). Until any further rulings come down--from the university's continuing inquiry or from the prosecutors, who are also looking into Hwang's allegations of cell switching at MizMedi--that...

Author: /time Magazine | Title: The Rise and Fall of the Cloning King | 1/1/2006 | See Source »

...rejected the role of aloof, inaccessible scientist to become a father-like figure for his young charges. And he introduced some genuine innovations into the science of cloning--gently squeezing the nucleus out of a donor egg rather than sucking it out violently and inserting the entire adult cell, not just its nucleus, into the hollowed-out recipient egg. Hwang insisted he had no interest in profiting from his discoveries; indeed, he turned over his patent rights to the university and the government...

Author: /time Magazine | Title: The Rise and Fall of the Cloning King | 1/1/2006 | See Source »

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