Word: celling
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Dates: during 1960-1969
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Coogan's Bluff, Siegel's latest film, will bolster his already exalted position among his followers, even though it may not do much to make his name a household word. Like most of the other 24 pictures he has directed (among them: Madigan, Riot in Cell Block 11), this one is the sort of gritty cops-and-robbers movie that audiences take for granted. Coogan's Bluff has all the qualities that distinguished Siegel's previous efforts: it is fast, tough and so well made that it seems to have evolved naturally, almost without benefit of cast, crew or rehearsal...
...done very good business, partly because the studio executives do not care for his bellicose, independent ways. "The brass made me put a prologue and epilogue on Invasion of the Body Snatchers that damn near ruined the whole thing," he recalls. "And after the first screening of Riot in Cell Block 11, all the executives filed out without saying a single word. I sometimes feel like a prophet without honor in my own land...
...already beat you,'" O'Conner said defiantly. "You can beat me physically, you can put me in that cell, but you've got to let me out sometime. Then I'm coming back here," he said...
...with another word. The words are read off continuously along a strand of DNA, much as a punched-tape message is read by a teletype machine. Among the 64 possible three-letter combinations of the four nucleotides, it was later discovered, there were several that served to direct the cell to start or stop manufacturing a protein. Nirenberg and Khorana also found some redundancy in the code: some of the amino acids were called up by several different three-letter combinations...
...Cornell, Holley studied both the genetic code and its function in building proteins by analyzing "transfer RNA," a form of ribonucleic acid. RNA collects amino acids floating in the cell and, like a tug towing a barge, pulls them to an assembly site where, in the sequence dictated by the master DNA molecule, they are combined into the appropriate protein. Holley worked out the complete structure of a transfer RNA molecule, demonstrating how it attaches to a particular amino acid and brings it to the growing protein chain at the proper time and place...