Word: celling
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Dates: during 1980-1989
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...front page and their successes on the sports page changed to a laugh last week when, in the same edition, several football agents, two boxers and a hockey player extended the fields of play to a grand jury room, an all-night boutique in Harlem and a prison cell...
...days after the story appeared, Martin was placed in solitary confinement. Prison officials said Martin was being investigated for "encouraging a group demonstration" and they feared "a threat to his safety" if he were free to circulate among other prisoners. Martin returned to his cell after 48 hours, but a week later he was transferred to a prison in San Diego, in preparation for yet another move to a facility near Phoenix. Fearing that Martin was beginning a regimen that inmates call "bus therapy" -- being transferred from facility to facility -- both Martin and the Chronicle filed suit against Rison...
...testing existing substances for their therapeutic effects, as was the case with AZT, the only AIDS drug approved for widespread use by the Food and Drug Administration. But recent advances in the field of molecular biology have given researchers a clearer understanding of the most minute workings of the cell. This has enabled them to engineer structures that can disrupt the cycle of a disease at the molecular level...
Developed by South San Francisco's Genentech, Inc., the CD4 currently in clinical trials is a copy of a protein that is anchored in the surface of cells known as T-4 lymphocytes. These cells are a pillar of the immune system and a key target for the AIDS virus. Natural CD4 attracts gp120, a molecule on the surface of the AIDS virus. In the usual course of the disease, the virus uses the natural CD4 to attach itself to a T-4 cell, which it invades and ultimately destroys. Synthetic CD4, however, acts as a decoy by latching onto...
...promise, no one expects that CD4 will cure AIDS. Yet the drug is a potentially important new weapon in a growing arsenal of treatments. Researchers are learning how to use AZT more effectively to interrupt the virus' life cycle inside a cell. Probably the best hope for a successful AIDS treatment lies in a combination of these and other drugs...