Word: celling
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...press conference to unveil a pro-life auto-license plate, Perry intimated that his potential opponent has been less than 100% supportive of pro-life policies. Hutchison, whose position on abortion has been described as "nuanced" by conservative columnist George Will, has supported federal funding for stem-cell research and opposed federal funds for abortion and late-term procedures, but she backed a 2003 Senate resolution endorsing the U.S. Supreme Court landmark Roe v. Wade ruling on abortion...
...therapy revolves around coaxing the stem cells to develop into a type of cell known as an oligodendrocyte, which in turn gives rise to critical insulation and growth factors that can repair neurons damaged by a trauma to the spinal cord. Geron has named its version GRNOPC1. By having more of these cells around the spinal cord, more nerves might be repaired and can then potentially re-establish proper connections. Simply by working with the GRNOPC1 cells, Geron scientists have learned more about how they operate, which will expand their understanding of how the central nervous system might be healed...
...trial will enroll patients with injury to the thoracic region, high in the spinal cord between the third and 10th vertebrae. Doctors will be trained to inject the cell treatment at specific locations, where the cells will remain to do their nerve-nurturing work. "I think it's incredibly exciting," says Dr. Susan Fisher, a stem-cell scientist and a professor of obstetrics, gynecology and reproductive science at University of California, San Francisco. "This really provides a blueprint for how to do these sorts of trials. It really proves the principle that these sorts of human embryonic-stem-cell therapies...
...that process wasn't such an easy hurdle to overcome. Because no one has used embryonic stem cells or the cells derived from them in people before, the FDA was particularly cautious. The trial that it approved is what's known as a Phase 1. It will involve no more than a dozen patients and is not designed to test the effectiveness of the cells. Rather, it will simply monitor the safety of inserting them into people. The researchers will be looking for whether the cells cause tumors, trigger an immune response or start to migrate away from the spinal...
...stakes all too well. He is a veteran of the last revolution in medical technology, gene therapy, which, after some hyped expectations in the 1990s, fell into disfavor after some unsuccessful trials. Crystal is cautiously optimistic about the potential for this trial to open the door to future stem-cell therapies. "I think this is a very positive start, but the expectations and hype I see around stem-cell therapies are the same that I saw around gene therapy. We just have to remember that these take a long time to develop. But you will never know if they work...