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Publishing in the Oct. 17 issue of the journal Cell, scientists at Rutgers University describe a group of antibiotic compounds, first isolated decades ago from naturally occurring antibacterial substances in soil. Among them, researchers say, is a compound called myxopyronin that shows great promise. It has been synthesized in the lab and shown to be safe in animal trials, and although the drug hasn't been tested in humans yet, cell-based experiments suggest that it is potent enough to kill a wide range of stubborn bugs, including drug-resistant strains of tuberculosis and the deadly type of staph known...

Author: /time Magazine | Title: A New Class of Antibiotics Could Offer Hope Against TB | 10/17/2008 | See Source »

...battle against drug-resistant tuberculosis, a disease for which clinicians have never had a perfect therapy. The success of TB treatment depends on the destruction of active and dormant bacteria to prevent relapse - something that few existing antibiotics have been able to do. One way to kill a dormant cell is to target biochemical processes that continue even in latency - there aren't many of those. But myxopyronin works by interfering with the enzyme RNA polymerase, which controls gene transcription in cells and is necessary for cell survival, dormant...

Author: /time Magazine | Title: A New Class of Antibiotics Could Offer Hope Against TB | 10/17/2008 | See Source »

...taken from her home in the GyeongSang province in southeastern South Korea to a Japanese military base in China. She said she was relocated several times before winding up at a comfort station in Manchuria where she lived until the end of the war, locked in a cell and raped repeatedly. “Five or six soldiers would come every day. Some insisted on not wearing condoms,” Kang said. “Once when I protested, he hit me hard on my head and broke my finger. From that day on my nose bleeds...

Author: By Carola A. Cintron-arroyo, CONTRIBUTING WRITER | Title: Former Sex Slave Speaks Out | 10/17/2008 | See Source »

Imagine sitting down in a theater, popcorn in hand. The lights dim, Kung-Fu Panda reminds you to silence your cell phone, and the previews start. But instead of the new Saw flick, a trailer for Culture and Belief 11: “Medicine and the Body in East Asia and in Europe,” plays across the screen, narrated by Shigehisa Kuriyama, a professor of East Asian studies. As the name implies, the class is a historical comparison of the body and medicine in East Asia and Europe, and its approach is anything but traditional. Kuriyama jettisons...

Author: By Alissa M D'gama, CRIMSON STAFF WRITER | Title: Gen Ed Course Swaps Podcasts for Papers | 10/17/2008 | See Source »

George Palade, a pioneer in cell biology, won the 1974 Nobel Prize in Physiology or Medicine for his work in isolating and identifying cell structure. His research, which he conducted along with biologists Albert Claude and Christian de Duve, used electron microscopy to identify the functions of mitochondria (the powerhouse of a cell) and ribosomes (proteinmakers), as well as other cell components. Having emigrated from Romania in 1946, Palade became chairman of the cell-biology department at Yale in 1973 and then the founding dean of scientific affairs at the University of California at San Diego...

Author: /time Magazine | Title: Milestones | 10/16/2008 | See Source »

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