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...these genes, two - clusterin and CR1 - are known to interact with the amyloid protein that builds up in the brain of Alzheimer's patients and eventually causes nerve cell death and cognitive problems. Clusterin may be involved in helping to clear away the amyloid that forms in the brain; but another variant of the gene may also allow amyloid to form fibrils, the sticky protein arms that further anchor amyloid plaques to nerve cells, much like a spider web ensnares prey. In late-onset Alzheimer's, it's possible that the body cannot balance these two functions of clusterin...

Author: /time Magazine | Title: Breakthrough Discoveries of Alzheimer's Genes | 9/7/2009 | See Source »

...other hand, the discovery of PICALM came as a bit of a surprise. That gene's activity affects the junction between nerve cells, where various neurochemicals work to relay signals from one nerve cell to another. While most of the research attention in Alzheimer's has been on the build up of amyloid protein and tau tangles that strangle nerve function, the identification of PICALM suggests that some part of the disease may have to do with a breakdown in nerve-cell communication at the junctures. "If you had given people a list of genes and said which ones were...

Author: /time Magazine | Title: Breakthrough Discoveries of Alzheimer's Genes | 9/7/2009 | See Source »

What's so great about Voice? It lets you centralize all your phone calls, which you can access from your home, office or cell phone. If you ignore a call, the voice mail is transcribed and sent to you as an e-mail, an SMS or both. Voice also lets you make free conference calls and cheap international calls...

Author: /time Magazine | Title: One Ring to Rule Them All | 9/7/2009 | See Source »

...with anything, practice makes perfect, which is reassuring for rookies - like me - who find it next to impossible to rein in their thoughts at first. During the course of one five-minute song, I thought repeatedly about whether I'd remembered to lock my car and turn my cell phone to vibrate. And, because I'm a reporter, I thought about what everyone else might be thinking about, which, if they were doing it right, should have been nothing...

Author: /time Magazine | Title: Samurai Mind Training for Modern American Warriors | 9/6/2009 | See Source »

iPhones • possible availability of to carriers other than the abysmal-service-providing AT&T means people may finally be able to have actual conversations on, which would be even more exciting if a new study hadn't just come out suggesting that cell phones cause brain cancer...

Author: /time Magazine | Title: This Preposterous Week! Paul Slansky's News Index | 9/4/2009 | See Source »

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