Word: cellular
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Dates: during 1960-1969
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Died. Sir Albert Edward Richardson, 83, British architect, onetime (1955-57) president of the Royal Academy of Arts, an 18th century addict who considered modern buildings "cellular facades cloaked with vitreous indifference," believed that "nothing should be streamlined except water closets," himself eschewed electricity and telephones, entertained in wig and knee breeches and paid calls on special occasions reclining regally in a sedan chair; of heart disease, in Ampthill, Bedfordshire...
...Today's biologist is bringing together the disciplines of the chemist, physicist, mathematician and many others, achieving thereby the unifying concepts of the cellular activity. We are entering a new world," Berry said, "as one can see brilliantly exemplified at the Brigham...
...particular interest is the mechanism called "repression"--a chemical feedback phenomenon that illustrates "intelligence" in cellular behavior. Cells that for some reason have changed or mutated--as in cancer--continue to produce materials they do not require. In normal cells an enzymatic feed-back or braking system slows or stops the production of these no-longer-needed materials...
...shown that the unit responsible for the transport of citric acid--essential for the combustion of fuels in all cells--across a cell membrane, can be altered by repression as well as by mutation. This discovery offers a powerful tool for approaching one of the least-understood aspects of cellular physiology--the remarkable capacity of cell membranes to select only certain substances for passage in and out of the cell...
...researchers went on to suggest that the specific arrangement of bases along the molecule constituted a code by which genetic information could be transmitted in cell division. This was the first major breakthrough in cellular biology--the first sound attempt to explain such important aspects of life as heredity in purely molecular terms...