Word: cellular
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Dates: during 1990-1999
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...decided that the old way of thinking about senescence needs to be challenged. In laboratories around the world, investigators are beginning to suspect, to their growing surprise and excitement, that what works in flies and worms may work for people too. From species to species, genus to genus, the cellular mechanisms responsible for aging appear to be the same. Armed with that knowledge, a new breed of longevity specialists is beginning to tease out answers to two of the great mysteries of life: Why do we age? And even more important, What can we do about...
...until all at once it stopped. From then on, the cells did something a lot like aging. They consumed less food; their membranes deteriorated; and the culture as a whole languished. Hayflick repeated the experiment, but this time used cells from a 70-year-old, and found that the cellular aging began a lot earlier, after 20 or 30 doublings. Clearly, it seemed, the cells from the older human were older themselves...
...What we were seeing," says Hayflick, now a professor at the University of California, San Francisco, "was the concept of cellular aging: growing old in the microcosm of a Petri dish...
...actuarial hourglass that gave it only so much time to live and no more. If the clock could be found--and, more important, reset--both the cells and the larger corpus that gave rise to them might be made immortal. Of course, hypothesizing the existence of such a cellular timekeeper was one thing; finding it and manipulating it were something else again. In the years since, senescence scientists have taken two approaches to achieving this goal...
Robert Reich is retiring for the best of reasons: he wants to spend more time with his family. He has found that balancing work and family is simply impossible. Not that he hasn't tried. We can imagine the poor sod, armed to the teeth with daily planners and cellular phones, trying to be there for everyone. Reich, our nation's Secretary of Labor, wrote of his decision to step down from the Cabinet for the Op-Ed page of the New York Times last Friday...