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Scientists think rapamycin's cellular target - called mTOR for "mammalian target of rapamycin" - helps regulate the body's response to nutrients and may also, according to Strong, "gear up responses to stress," such as the oxidative stress that damages proteins and DNA and contributes to disease development. "What we're doing with rapamycin," Strong says, "is we're actually tricking the cells into thinking that they're depleted of nutrients. Rather than the animals losing weight - we haven't noticed any weight loss - they may be just using their proteins more efficiently, and then repairing proteins more efficiently...

Author: /time Magazine | Title: What Does Life-Extending Drug Mean for Humans? | 7/9/2009 | See Source »

...this cellular efficiency, perhaps, that delays aging and helps preserve animals' good health. The findings suggest that rapamycin does not affect or prevent any one disease specifically - the mice in the study died of various causes, with no real difference between mice that received rapamycin and those that didn't - but rather that it slows aging overall. (Read a TIME cover story on the science of aging...

Author: /time Magazine | Title: What Does Life-Extending Drug Mean for Humans? | 7/9/2009 | See Source »

When he formulated the idea for the DynaTAC, Motorola's prototype for the first cellular phone, John F. Mitchell, who died on June 11 at 81, boasted that his creation would be useful to a "widely diverse group of people--businessmen, journalists, doctors, housewives, virtually anyone." But back in 1973, Mitchell--then chief engineer of the company's mobile- and portable-products division and later the company's president and chief operating officer--probably had no idea that by the time he retired, in 1998, wireless products would account for two-thirds of Motorola's $30 billion in annual sales...

Author: /time Magazine | Title: John F. Mitchell | 7/6/2009 | See Source »

Apple's newest iPhone offers the holy grail of the cellular business: help for when you misplace the device. The Find My iPhone feature lets you locate it on a Google map and then make it beep until you pick it up. You can also send a message to display on its screen if the phone is far away--say, in a restaurant. Or if it gets stolen out of your hands (as Kevin Bacon's BlackBerry was last month), you can erase everything on your phone remotely. But the feature isn't free: it's part of Apple...

Author: /time Magazine | Title: iLost My Phone | 6/29/2009 | See Source »

...tethering. Use your iPhone like a wireless modem and connect a laptop to it. Never pay for wi-fi at a hotel again! At least, that's the promise of this technology. In reality, we have no idea what U.S. cellular partner AT&T will charge users; AT&T hasn't even said yet when it will open its network to this feature...

Author: /time Magazine | Title: iPhone's New Operating System: A Snappy Upgrade | 6/18/2009 | See Source »

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