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...1990s, he and ADARC established themselves as leaders in the AIDS field by pioneering the early use of the antiretroviral (ARV) cocktails that have reduced the death rate from AIDS (for which Ho was named TIME's Person of the Year in 1996). But in recent years, the center has suffered a series of setbacks, including a scientific paper that required a partial retraction, and the departure of key scientists. These challenges have some in the field wondering whether ADARC - and its golden-boy director - are on the verge of the next big breakthrough in AIDS or are wandering down...

Author: /time Magazine | Title: David Ho: The Man Who Could Beat AIDS | 1/25/2010 | See Source »

Without an answer, developing vaccines is a very halting process. "The virus is a moving target," says Dr. Gary Nabel, director of the Vaccine Research Center at the National Institutes of Health (NIH). "It is constantly changing its genetic makeup through mutations. It's also a moving target because the proteins of the virus surface are actually moving themselves - they are conformationally flexible. The net result is that the immune system never gets a really good look at them...

Author: /time Magazine | Title: David Ho: The Man Who Could Beat AIDS | 1/25/2010 | See Source »

...didn't take long before these futile efforts began to wear on the researchers in the field, not least of all those at ADARC, where Ho's group was attempting to develop its own vaccine - with little success. The center - which had earned such laurels for its ARV triumph - began to suffer a scientific slump and lack of direction, according to those who left in the early 2000s. Some blame Ho's management style, which, they say, changed in the aftermath of media attention that came with his recognition as Person of the Year. They describe a highly competitive atmosphere...

Author: /time Magazine | Title: David Ho: The Man Who Could Beat AIDS | 1/25/2010 | See Source »

...They play with a lot of heart, considering the stuff that’s been going on with their team,” sophomore center Keith Wright said...

Author: By Dennis J. Zheng, CRIMSON STAFF WRITER | Title: Crimson Survives in Ivy Road Opener | 1/25/2010 | See Source »

...Crimson traveled to the Burrow-Burleson Tennis Center in Blacksburg, Va., to take part in a round-robin weekend tournament, which also featured No. 23 Auburn University, No. 27 Virginia Tech, College of Charleston, and Indiana University. Day one was not kind to Harvard, as the squad fell in 10 out of 12 matches to the highest-ranked opponent at the competition. But the Crimson fought back throughout the weekend, recording several key wins to keep the team in the tournament...

Author: By Brian A. Campos, CRIMSON STAFF WRITER | Title: Men's Tennis Shows Promise Against Top Squads at Hokie Challenge | 1/25/2010 | See Source »

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