Word: cervarix
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...Morton died after receiving GlaxoSmithKline's Cervarix, one of two vaccines designed to protect women from the human papillomavirus (HPV), a sexually transmitted infection linked to most cervical cancers. (American women receive Gardasil, an HPV vaccine manufactured by Merck.) Introduced last year, Cervarix is expected to cut deaths from cervical cancer in Britain by about 75% - or 650 deaths a year. So far, the vaccine has been given to 1.4 million women in Britain, and Morton's death is the first to be possibly linked to the shot. But there have also been less serious side effects in recipients. Britain...
...study in the Aug. 15 issue of the Journal of the American Medical Association aims to clear up at least some of that uncertainty. Dr. Allan Hildesheim, an epidemiologist at the National Cancer Institute, and his colleagues set out to determine whether Cervarix - a new HPV vaccine for which GlaxoSmithKline hopes to get federal approval in early 2008 - could help reduce the virus-load in women already infected with HPV. According to the study's authors, past trials have suggested that HPV vaccination boosts the body's immune response to infection, and some researchers thought that it might work...
...field of HPV vaccine research is still in its earliest stages. Studies have only just begun on the safety of the vaccine in women older than 26. And, according to GlaxoSmithKline spokeswoman Liad Diamond, studying Cervarix in boys and men is "on the radar screen of the clinical development team" but there is "nothing underway right now." At Merck, clinical trials of Gardasil in males have been ongoing for about a year, and preliminary results show that "immune responses in 9- to 15-year-old boys are consistent with those found in females aged 16 to 23," according to Merck...
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