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More than half of the $7.1 billion that President Bush wants to spend preparing for a flu pandemic is dedicated to finding better ways to make antiviral drugs and vaccines, an investment that scientists say is long overdue. Flu vaccines were being grown in chicken eggs more than 50 years ago, and that's how they're still made today. It's a painfully slow procedure that takes about nine months, with much of that time devoted to the hit-or-miss process of incubating viruses in the chicken eggs...
...work won't be wasted. The upgrade will make even the annual flu vaccines more effective and will prepare us better for when the next pandemic threat looms. CURRENT METHOD: EGG CULTURE Virus is purified and chemically killed to produce the vaccine Virus --> Virus is grown in fertilized chicken eggs --> Vaccine NEW METHOD: HUMAN-CELL CULTURE Virus is killed and processed to produce the vaccine Virus --> Cell --> Virus is grown in human-cell culture --> Vaccine GENETIC METHOD: DNA VACCINES Plasmid is manufactured, purified and painted onto gold particles Virus --> Viral RNA --> Microscopic gold particles --> Gene gun shoots particles into...
Bombay may be india's hippest city, but until recently finding a decent international restaurant outside the top hotels was a challenge. Visitors wanting a change from local cuisine and hotel food resorted to fast-food chains or pseudo-Chinese diners, where the ubiquitous "Chicken Manchurian" provided a spectacular example of the perils of fusion cooking. But Bombay is now finally getting the culinary makeover it has long deserved. And what Bombay does, the rest of India follows. Here's our pick of the city's best non-hotel venues: INDIGO The first classy independent restaurant in India when...
...inside out on Tuesday, when short-term interest rates inched higher than long-term interest rates. That's not the natural order. On Wall Street, this rate flip-flop is known as an inverted yield curve. It's a relatively rare occurrence, and one that always drags out economic Chicken Littles. But the sky is not falling on this expansion just...
...What's abnormal today is how low long-term rates have remained, explained at least in part by China's and Japan's historic demand for Treasury bonds. Absent unprecedented foreign demand, Treasury bond yields likely would be well above short-term yields today-and Chicken Little would have no audience. That's not to say the yield curve won't invert again, and grow more pronounced. If it does, be warned. But we're not at the breaking point today, and may not get there for years...