Word: childrene
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...Consumers are willing to pay for convenience, say the experts, especially when grabbing items that they really need. "Is it a good idea? It's the only idea," says Howard Davidowitz, chairman of Davidowitz & Associates, a retail consultancy and investment bank. "Mothers are going to the store with their children, and to the extent you give mothers another reason to shop, you win. I compliment them for reacting. Doing nothing is not an acceptable answer." (See 10 things to buy during the recession...
...weren't customers shopping for snacks at Toys "R" Us? First of all, some mothers simply refuse to torture their children. Think about it: you're a kid. You take a trip to heaven, a.k.a. Toys "R" Us, once every two months or so. And with all those bikes, trains and video games surrounding you, Mom brings you to the Clorox aisle? Talk about temper-tantrum central. "As you can see, he doesn't want to be here," says Jennifer Meade, whose 7-year-old son Logan is fiddling with a Nerf Blaster in a shopping cart, looking like...
Eileen Muniz of Mohegan Lake, N.Y., cannot imagine what bizarre twist of fate caused all three of her children to be afflicted with autism spectrum disorders. There's no family history of autism, she says. "You always ask yourself, Is it me? Is it him [her ex-husband]? I had my kids late - in my mid-30s. Was I on the birth control pill too long? I never did drugs. I don't smoke. I can't figure out why this would happen to us. That's why I wanted to do the genetic testing...
Muniz, her ex and her children are among the 2,025 families who volunteered to be genetically tested for a vast registry called the Autism Genetic Resource Exchange (AGRE), assembled to help researchers untangle the complex genetics of autism. Now that effort is beginning to pay off. The largest genetic study of autism ever attempted - involving more than 3,000 participants from AGRE, 1,453 cases from other sources and over 7,000 additional control subjects - identified genetic variations in a region of chromosome 5 that appears to play a pivotal role in about 15% of cases of autism. What...
...sticky substances involved in a process known as neuronal cell adhesion. "They sit at the synapse, and when the nerves come together, these molecules adhere to the nerve," essentially fusing a connection in the brain, explains Dr. Hakon Harkonarson, director of the Center for Applied Genomics at the Children's Hospital of Philadelphia (CHOP) and a lead author of the study. Preliminary research suggests that cadherin 10 is very active in wiring the frontal cortex of the brain during fetal development...