Word: chiron
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...concerns that seem to show the most promise. "Many, many companies have scrambled to get into the race," notes Ed Hurwitz, an analyst for Robertson, Stephens & Co. The list of recent mergers, as Hurwitz ticks them off, reads like a Who's Who of biotechnology: "Sandoz buys Genetics Institute. Chiron buys Viagene. Bristol Myers makes a big investment in Somatix. Merck makes a big investment in Vical. Rhone-Poulenc invests in Applied Immune Sciences and several other gene-therapy companies...
...results from the clinical trial in which Arens has been participating. The study showed that patients receiving a recombinant form of beta interferon did better than those getting the placebo. The difference was quite dramatic for those patients who received high dosages of the drug, which is manufactured by Chiron Corp. and Berlex Laboratories. Compared with the control group, high- dose patients suffered 50% fewer serious attacks of the disease, and those attacks were of shorter duration. Moreover, brain scans revealed that this group of patients incurred fewer central nervous system lesions, suggesting that the therapy may be more than...
Hepatitis C afflicts an estimated 150,000 Americans each year. The virus, like type B, is spread primarily by sexual activity and through tainted blood in transfusions or on addicts' dirty needles. (Hepatitis A is passed along mainly through contaminated foods.) Researchers at Chiron Corp., a biotechnology firm in Emeryville, Calif., that first identified the C virus, have devised a test for the pathogen that can be used to screen the blood supply...
This last major threat in the U.S. blood supply may soon be greatly reduced. After six years of research, scientists at Chiron, a genetic-engineering firm in Emeryville, Calif., have developed a test for the presence of a non-A, non- B hepatitis virus in blood samples. According to papers published last week in the journal Science, trials have shown that Chiron's test is highly reliable. It can now help eliminate the virus from the blood supply. The inexpensive test (about $2 per blood sample) is expected to be approved by the Food and Drug Administration this year...
...Chiron's initial breakthrough was to isolate a viral protein from blood samples taken from patients with non-A, non-B hepatitis. By cloning large quantities of the protein, the company was able to develop a test to detect its presence in blood. Chiron called the pathogen the "hepatitis-C virus." In clinical studies done at the National Institutes of Health, the Centers for Disease Control and laboratories in Italy and Japan, blood samples from patients thought to have non-A, non-B hepatitis were screened using Chiron's test. At least 80% of the samples tested positive...