Word: cholecystokinin
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Dates: during 2000-2009
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...might expect, the short-term signals are involved mostly with the initiation and completion of meals. Ghrelin, a hormone produced by the stomach, tells the brain, "It's time to eat!" When enough food leaves the stomach and reaches the small intestine, another hormone, called cholecystokinin, signals that the meal is over--and triggers the release of enzymes in the gallbladder and the pancreas...
...eating side, researchers at Glaxo are studying cholecystokinin, which is released by the intestines after a meal to signal the brain that the body has had enough. Giving obese patients a synthetic form of cholecystokinin before meals tricks the body into feeling full, so patients eat less. About 25% of the participants in an early trial lost almost 7 lbs. in the first eight weeks...
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