Word: cholesterol
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Dates: during 1930-1939
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...lectured at the University of Chicago this summer. In 1931 Dr. Adolf Butenandt of Danzig discovered in the urine of men (and some women) the hormone which establishes masculinity in men (and some women). That male sex hormone was named androsterone. Last year Professor Ruzicka manufactured androsterone from cholesterol collected from the grease of sheep's wool. Last June Dr. E. Laqueur of Amsterdam discovered still another, more potent male sex hormone. Professor Ruzicka now expects to make the Laqueur sex hormone artificially "within a few weeks...
...triumph. In the past he showed that the Chinese shrub Ma Huang was good, ancient medicine because the ephedrine which it contains relieves congestion in cold-ridden noses and stimulates poky hearts. He showed that toad venom was good, ancient medicine because it contains unusual concentrations of cholesterol, ergosterol, bufagin, bufotoxin and bufotenine...
...then other hormones have been refined and analyzed. Last week Professor Leopold Ruzicka of Zurich significantly reported in Nature that he had synthesized the male sex hormone. To get it, this altogether reputable scientist attacked hydroxy-ketone, a substance related to acetone, with dihydrocholesterol which is a derivative of cholesterol found in bile, brains and eggs. Nicely controlled chemical procedure produced a modified hydroxy-ketone which he claims is chemically identical with the male sex hormone. Whether it can be used alone or whether, like natural sex hormones, it works best in combination with pituitary, thyroid or adrenal cortex medication...
Vitamin D, the vitamin which controls the growth of bones, prevents rickets, is formed by sunlight acting on ergosterol, a vegetable substance. Chemical twin of ergosterol is cholesterol which is involved with the female sex hormone theelin. Sex hormones are intimately connected with growth, and so the "sterols" may be a foundation for all kinds of growth...
...uses of adversity, which like the toad, ugly and venomous, wears yet a precious jewel in his head (As You Like It). From glands located behind the eyes of 7,500 U. S., German, Jamaican, Uruguayan, South African, Chinese and Japanese toads. Dr. Chen extracted potent drugs (adrenalin, cholesterol, ergosterol, and two digitalis-like substances) which modern scientific medicine considers indispensable. Apparently toads do not use these potent drugs in their own economies. When Dr. Chen removed the glands from several toads, they seemed as well as ever, pursued their proper business of bug hunting. Prospective toad farmers should note...