Word: cholesterol
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...genetic effect,” said Medical School professor Alessandro Doria, the director of the Genetics Core at Harvard-affiliated Joslin Diabetes Center. According to Doria, diabetes accounts for many coronary artery disease cases. “Other factors of coronary artery disease include smoking, hypertension, and high cholesterol,” Doria said. “Over the years these factors have gone down while diabetes has not. In fact, diabetes rates are increasing.” The study, which included more than 1,500 type 2 diabetes patients over several years, surprised both Doria and his colleagues...
...According to the pharmaceutical market news service Pharmawire, around $114 billion worth of drugs will go off patent in 2008-12, including lucrative brands such as Eisai's Aricept, which treats Alzheimers, and Pfizer's Lipitor, which lowers cholesterol. Some analysts say patent expirations could lead AstraZeneca and GlaxoSmithKline to lose up to one third of their sales...
Four hundred fifty thousand people will die this year of coronary heart disease, according to the National Heart, Lung, and Blood Institute, and half of them will be healthy individuals who do not have high levels of cholesterol...
...Several years later, Ridker and his colleagues at the Medical School and Brigham and Women’s have released the results of a study testing the effectiveness of the cholesterol-lowering drug rouvastatin in treating individuals with high levels of a reactive protein that is an indicator of heart disease...
...study, funded by Astra-Zeneca, the maker of rouvastatin, tested nearly 18,000 patients who had low levels of cholesterol but high levels of the reactive protein. According to Ridker, the reduction in heart disease risk was far greater than the researchers anticipated...