Word: cholesterol
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...people in the new study, who will be drawn from the U.S., Canada, Eastern Europe, Australia and South America, will be randomly assigned a regimen of either Celebrex, ibuprofen or naproxen. They will also take aspirin, cholesterol-lowering drugs and other medications appropriate for heart patients, as well as a drug to prevent stomach bleeding, which all three of the painkillers may cause. The four-year study should be sufficient time to reveal what risk, if any, the cox-2s pose, but it could end sooner if one of the medications reveals itself as just too dangerous...
...disease; in Naples, Fla. Dawber recruited 5,209 healthy men and women to follow in a long-term study that led to key findings, including those in a 1961 landmark paper that isolated such "risk factors" (a term Dawber coined) for heart disease as high blood pressure and high-cholesterol levels. A few years later, he rescued the Framingham study--which the government was considering shutting down--by raising money to continue the research and facilitating the study's partnership, still in effect, with Boston University...
...while the new antipsychotics can easily run 4 to 10 times as much or more. Zyprexa, a fourth atypical antipsychotic included in the study, helped more patients for longer than the other drugs, but it was also more likely to cause severe weight gain, high blood sugar and high cholesterol. By the end of the study, 74% of patients had abandoned their medicines because they either didn't work well enough or caused intolerable side effects...
STATINS The more than 10 million Americans who take statin drugs to lower cholesterol may be enjoying some unexpected benefits. New studies suggested that regularly taking medicines like Lipitor, Lescol, Pravachol and Zocor may halve a patient's risk of developing colon and advanced prostate cancers while reducing their risk of pancreatic and esophageal cancers more than 50%. Another study showed that patients who aren't on statins can cut their risk of death following a heart attack more than 50% if they take them before hospitalization and within 24 hours after the attack. Doctors think the cholesterol- and inflammation...
...linked to the disorder] could lead us to information that could lead us to discover remedies.” The variants associated with bipolar disorder will not definitively indicate that someone will have the disease, she said, but will signal an increased risk for the disorder, much like high cholesterol indicates an elevated risk for heart disease. Diabetes and bipolar disorder are only two of the diseases being studied. In the Boston area alone, researchers are using similar genetic methods to learn more about autism, multiple sclerosis, and heart disease, Altshuler said. Altshuler said it remains unclear how fruitful this...