Word: cholesterols
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Dates: during 1980-1989
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Once filled, the HDL particles must get their load of cholesterol back to the liver for excretion. Some researchers theorize that cholesterol collected in the HDL particle is transferred to a VLDL ferryboat circulating in the bloodstream; the VLDL then metamorphoses into an LDL, which is picked up by an LDL receptor in the liver. Others think HDL may in fact be a passive player -- a sort of biological signal light that indicates how efficiently excess cholesterol is being removed, without necessarily taking any direct role...
...actually does have the ability to pull cholesterol out of artery walls, can high levels of HDL reverse the buildup of plaque? There are indications that this may be the case. Last year Dr. David Blankenhorn, director of atherosclerosis research at the University of Southern California, reported on a study in which 162 nonsmoking men who had undergone coronary- bypass surgery were put on a low-fat diet; 80 of them were also treated with niacin and colestipol. Among the drug-treated group, HDL levels increased 37%, while LDL decreased 43% and triglycerides went down 22%. Blankenhorn found evidence that...
This week's cover stories on "good" cholesterol nearly created a crisis in the home of senior writer David Brand, who wrote both the main story and the accompanying article on nutrition. Brand became so intrigued by the topic that he began to analyze the cholesterol content of all the meals his family ate. "That nearly drove my daughters Leslie and Robyn crazy," he recalls. "They accused me of ruining every meal and wanted to ban the subject altogether." Never an autocrat at the table, Brand capitulated in the interest of domestic peace...
...paper's front page, he went to London as a Journal correspondent. Among his assignments was a visit to Siberia to report on Soviet science. He joined TIME as a senior editor in 1983, where one of his first duties was editing a cover article on the dangers of cholesterol. Eighteen months ago, Brand returned to his first love, writing, and has since applied his curiosity to such subjects as Asian-American students, the environment and the hospice movement. In preparation for this week's stories, Brand so immersed himself in the subject that he even had his own cholesterol...
...main street, baseball field and grassy square, Wellsburg, W. Va., is in many ways a typical American town. Perhaps too typical. A survey last spring found that almost 70% of the Wellsburg area's 11,000 residents were at risk for heart disease. "I was just shocked that my cholesterol was that high," says Kitty Weidner, 75, whose reading was 241 milligrams per deciliter (mg/dl) of blood. Admits store owner Tom Zurbuch, 46, a former junk- food junkie whose cholesterol level was about 265: "Apparently, we haven't been eating right...