Word: chorea
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Dates: during 1980-1989
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Cystic fibrosis, cleft palate, muscular dystrophy, Alzheimer's disease, Huntington's chorea. The list of disorders that have been traced to a specific gene or gene region seems to grow on a weekly basis. The latest in this gene- of-the-week series: the discovery of a region on the X chromosome that is linked to manic depression, a mental disorder that affects as many as 2 million Americans. The finding, published in Nature by an American and Israeli research team, was based on studies of five families in Jerusalem. It marks the second time in three weeks that...
...some researchers believe, may lead to a cure for Parkinson's disease within five to ten years. Eventually, it may also become possible to repair the spinal cords of paraplegics and regenerate parts of the extensively damaged brains of patients with Alzheimer's disease, Huntington's chorea, multiple sclerosis and other degenerative disorders...
...Americans); Prader-Willi syndrome, a children's ailment that causes huge weight gains and often kills its victims before they are 20 (2,000); Wilson's disease, a condition marked by abnormal accumulation of copper in the liver and brain (1,000); Huntington's chorea, the degenerative disease of the mind and nervous system that caused the death of Folk Singer Woody Guthrie (14,000); as well as various rare cancers...
...rate during the manic phase. (No pattern has been found for the depressive phase.) People with senile dementia show decreased glucose metabolism; the more advanced the case, the lower the activity. Researchers also plan to use PET for biochemical brain portraits of patients with multiple sclerosis, Huntington's chorea and possibly alcoholism...
Since scientists first began manipulating genes, they have been envisioning a brave new world in which diseases from Huntington's chorea to sickle-cell anemia to possibly diabetes could be cured simply by inserting the correct strip of DNA into the body's cells. So far, though, most of the genetic tinkering has been limited to transplanting genes into isolated cells in laboratory dishes or into bacteria...