Word: chronic
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...with about 10% to 15% of Americans, mostly middle-aged or older, suffering from chronic pain severe enough to interfere with daily life, figuring out which pain medications work best - and which are safest - is of crucial interest. That's why researchers have recently been taking a closer look at the class of drugs called opioids, which includes codeine, morphine and methadone - medicine's oldest and most powerful pain medications...
...review published in the Jan. 20 issue of the Cochrane Database of Systematic Reviews, a leading evidence-based-medicine journal, researchers found that only one-third of 1% of chronic-pain patients without a history of substance problems became addicted to opioids during treatment. The review included 4,893 mostly middle-aged chronic-pain patients, who were treated with opioids for between six months and four years. "This suggests that people who do not have a history of drug abuse or addiction are not highly like to develop [addiction] under physician care," says Meredith Noble, lead author of the review...
...Overdose Problem For the most recent study of overdose risk, researchers examined the medical records of nearly 10,000 chronic-pain patients being treated within a Washington State health plan between 1997 and 2005. Published in the Annals of Internal Medicine in January, the study found that 51 patients had experienced overdose - six of them fatal. The overall risk of overdose was small, but it was clearly associated with the dose of the medication originally prescribed: patients receiving the highest doses were nearly nine times more likely to overdose than patients on the lowest doses. "The overall risk among people...
...This is hardly the first time the world has heard renaissance rhetoric about Haiti, a republic long crippled by chronic political and natural catastrophes. And experts say it will take far more than just new agribusiness, especially housing and manufacturing, to make the relocation plan anything besides a pipe dream. But Bellerive - who along with the head of state, President René Préval, last week hosted Nicolas Sarkozy in the first ever visit to Haiti by a French President - sees an unusual air of cooperation between Haiti and the international community now. That, he hopes, will create "more...
...confusing the vote will be - in the south, voters will be asked to cast 12 separate votes for various national and regional institutions - and the competence of the election officials. And a poll alone can hardly turn the south into a fully functioning nation. After decades of war and chronic underdevelopment, David Gressly, the U.N.'s regional coordinator for southern Sudan, reckons that it will take billions more dollars in aid and another "10 to 15 to 20 years" of international assistance to get the place on its feet. But after more than half a century of suffering in Sudan...