Word: chronical
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Dates: during 2000-2009
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...Oscar. He already is due to show up later this month at the Golden Globes (another Traffic nomination). If he wins, he can put that gewgaw next to his older Independent Spirit Awards for his turns in The Usual Suspects, as a crook with a bad attitude and a chronic case of the mumbles, and Basquiat, where he uttered the immortal threat, "What would you do if I kissed ya?" Swoon, maybe, since Del Toro has a sexy smile, when he can summon the energy to flash...
...compared epibatidine with several hundred related compounds they had synthesized as experimental treatments for Alzheimer's disease. One of them, ABT-594, turned out to be remarkably similar but much less toxic. Tests on animals indicate that ABT-594 is about 50 times better than morphine in relieving both chronic and acute pain yet seems to be nonaddictive. Phase II tests on humans should be completed by the end of the year...
Each species of cone snail produces a unique venom that contains between 50 and 200 pharmacologically active peptides known as conotoxins. The most advanced conotoxin-derived drug in development is Elan Corp.'s Ziconotide, a nonaddictive treatment for severe chronic pain that is awaiting FDA approval. Cognetix, based in Salt Lake City, Utah, recently started clinical trials on a possible epilepsy treatment. Also in the works: potential therapies for schizophrenia, stroke and Parkinson's and Alzheimer's diseases...
...pain for fear of being labeled cranky or difficult or because they assume that their discomfort will go away. And yet, says June Dahl, professor of pharmacology at the University of Wisconsin, that reluctance can backfire. Left uncontrolled, the pain you thought was temporary can trigger a long-term chronic condition. It can also interfere with the healing process and lengthen your recovery time...
BATED BREATH The use of inhalers containing corticosteroids is one of the most common treatments for chronic bronchitis and emphysema. Now doctors report that while the steroids may improve symptoms like shortness of breath and even reduce doctor visits, they fail to slow the progression of these smoking-induced diseases. And there are side effects, like bone loss. Don't toss the inhalers; talk to your doctor...