Word: chronicic
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...hopes and partly because doctors are increasingly convinced that a cure is not the only way to beat cancer. Instead, experts believe, by throwing a series of monkey wrenches into the cancer cell's machinery, the new therapies could transform cancer from an intractable, frequently lethal illness to a chronic but manageable one akin to diabetes and high blood pressure. Says Dr. Leonard Saltz, a colon-cancer specialist at Memorial Sloan-Kettering: "I don't think we're going to hit home runs, but if we can get a series of line-drive singles going and put enough singles back...
...Cambridge, Massachusetts, Millennium Pharmaceuticals is focusing on proteins called proteasomes, which evidently play a role in giving cancer cells unnaturally long lives. The company is in Phase II trials with LDP341, a proteasome-inhibiting substance that is showing promise against multiple myeloma and chronic lymphocytic leukemia. Phase I studies on the top five solid tumors (breast, pancreatic, prostate, lung and colon) are under way, and at this point the inhibitor seems to be working?at least in mice...
...February of last year, Victoria Reiter, 63, figured she had only a few months to live. A writer and translator living in Manhattan, she was suffering from chronic myeloid leukemia, an especially deadly form of blood cancer. The only treatment available was interferon, an immune-system booster that wasn't really working and that made her violently ill. Reiter had spent most of 1999 in bed, too sick to read, to walk, to do much of anything--although she had managed to put together lists dividing her possessions between her two daughters...
...hopes and partly because doctors are increasingly convinced that a cure is not the only way to beat cancer. Instead, experts believe, by throwing a series of monkey wrenches into the cancer cell's machinery, the new therapies could transform cancer from an intractable, frequently lethal illness to a chronic but manageable one akin to diabetes and high blood pressure. Says Dr. Leonard Saltz, a colon-cancer specialist at Memorial Sloan-Kettering: "I don't think we're going to hit home runs, but if we can get a series of line-drive singles going and put enough singles back...
...Cambridge, Mass., Millennium Pharmaceuticals is focusing on proteins called proteasomes, which evidently play a role in giving cancer cells unnaturally long lives. The company is in Phase II trials with LDP341, a proteasome-inhibiting substance that is showing promise against multiple myeloma and chronic lymphocytic leukemia. Phase I studies on the top five solid tumors (breast, pancreatic, prostate, lung and colon) are under way, and at this point the inhibitor seems to be working--at least in mice...