Word: citalopram
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...STAR*D patients were taking citalopram, an SSRI marketed in North America as Celexa. Not surprisingly, those who met standard inclusion criteria for a clinical trial had significantly better outcomes on the drug. In the efficacy group, 52% responded to Celexa vs. 40% of the nonefficacy group. Patients in the latter group also took longer to respond and had to be readmitted to psychiatric settings more often. "Thus," the authors conclude, "current efficacy trials suggest a more optimistic outcome than is likely in practice, and the duration of adequate treatment suggested by data from efficacy trials may be too short...
...manner of death" was summed up at the end of the 12-page autopsy: "Accident." But when he died, Cassidy had the contents of a locked medicine cabinet coursing through his body, powerful narcotics and other drugs like citalopram, hydromorphine, morphine and oxycodone, as well as methadone. The drugs--both the levels that Cassidy took and "their combined, synergistic actions," in the medical examiner's words--killed...
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