Word: citron
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Dates: during 1990-1999
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...those who entered the race was molecular biologist Martin Citron. In 1997, shortly after he moved from Harvard to Amgen, in Thousand Oaks, Calif., he and his team began a long, painstaking elimination process by inserting active human genes, in strings of 100 at a time, into living bacterial cells. When the team found cells making more amyloid protein than might have been expected, it narrowed the strings to 20 genes and repeated the process. Finally, the Amgen team zeroed in on the single gene responsible for producing the extra amyloid. Having found the culprit, the researchers went...
...next step is to turn this laboratory triumph into a medication--one that can stop the enzyme without causing disastrous side effects. That won't be easy, and, as Citron points out, it won't happen overnight. Nor will the Amgen scientists lack for competition. Even as their Science paper appeared, other drugmakers indicated they were hot on the trail of the enzyme as well. And while Alzheimer's researchers offered the usual caveats, they seemed almost unanimously agreed that the identifying of the shadowy enzyme was not only a potential bonanza for drug companies but also the first really...
...idea where yellow was going, but I knew where it had been. My bedroom. My foyer. And the master bath, even the guest room. In fact, a recent freshening of our apartment decor had left it awash in pale, burnished aureoles of ocher and flax and citron and other members of the yellow family, all of them, amazingly, on speaking terms. Having surrendered palette control to my spouse, who in turn capitulated to professional direction, I suddenly found myself surrounded by--and bonding with--a spectrum of hues I had always held in special contempt...
SENTENCED. ROBERT CITRON, 71, former Orange County, California, treasurer; to one year in prison and a $100,000 fine; for securities fraud and misuse of public funds that led to a $1.7 billion loss in 1994; in Santa Ana, California...
...David each face a maximum sentence of two-and-a-half years in a house of corrections for each of the first two counts; one year for the third and fourth counts; and two-and-a-half years for the last two counts, Assistant District Attorney Kenneth E. Citron said yesterday...